Background
A neurobiology-focused client offering phenotypic and target-based assay development, screening, and lead optimization faced increasing demand for neuronal cells derived from various human pluripotent stem cell (hPSC) lines. To meet customer needs, they required support in scaling up and banking neuronal progenitor cells efficiently and consistently.
CCRM Nordic’s Approach
CCRM Nordic applied its extensive experience in stem cell scale-up, differentiation, and cryopreservation to develop a robust manufacturing strategy. By transferring and refining the client’s existing protocols, we provided technical input on optimal scale-up parameters and process standardization to ensure reproducibility and efficiency.
Results and Impact
Together with the client, we established a scalable and controlled workflow for neuronal cell banking. The resulting process enhanced production efficiency, improved cost control, and enabled more predictable planning. This project showcases how CCRM Nordic’s technical expertise and process development capabilities help industrial partners meet growing demand for advanced cell models.